Sergey V. Shirshev
Address
15 Bukireva, Perm 614990, Russia
Perm State University
Faculty of Biology
Department of Microbiology and Immunology
Phone, Fax, e-mail
tel: +7-(342)- 280-84-31, fax: +7-(342)- 280-92-11, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Date of Birth
28.05.1960.
Educational Background
Speciality “Hygiene and Epidemiology”, Faculty of Sanitary and Hygiene, Perm State Medical Institute, 1984.
Graduand of Post-graduate Study, Perm State Medical Institute, 1984-1988.
Doctoral Course - Institute of Ecology and Genetics of Microorganisms at the Ural Branch of the Russian Academy of Sciences, 1993-1996.
Scientific Degrees and Titles
Candidate of Medicine. Chelyabinsk State Medical Institute, 1989.
Senior Research Fellow. Institute of Ecology and Genetics of Microorganisms at the Ural Branch of the Russian Academy of Sciences (Perm), 1995.
Doctor of Medical Sciences. Institute of Immunophysiology (Moscow), 1996.
Professor. 1998.
Stages of Professional Career
Senior Laboratory Assistant. Department of Biochemistry, Perm State Medical Institute, 1984-1990.
Assistant Lecturer. Department of Immunology and Department of Biochemistry , Perm State Medical Institute, 1990-1993.
Reader. Department of Zoology of Vertebrates, Perm State University, 1991-1994.
Reader. Department of Microbiology and Immunology, Perm State University, 1994-1996.
Assistant Lecturer. Department of Pathological Physiology, Perm State Medical Academy, 1993-1995.
Senior Research Fellow. Institute of Ecology and Genetics of Microorganisms at the Ural Branch of the Russian Academy of Sciences (Perm), 1993-1997.
Senior Lecturer. Department of Pathological Physiology, Perm State Medical Academy, 1995-1997.
Professor. Department of Microbiology and Immunology, Perm State University, 1996 till present date.
Head of Laboratory of Ecology and Genetics of Microorganisms, Institute of Ecology and Genetics of Microorganisms at the Ural Branch of the Russian Academy of Sciences (Perm), 1997.
Head of Laboratory of Immunoregulation, Institute of Ecology and Genetics of Microorganisms at the Ural Branch of the Russian Academy of Sciences (Perm), 2007 till present date.
Professor. Department of Physiology of Plants and Microorganisms, Perm State University, 2008 till present date.
Membership in Scientific Councils, other State and Public Associations
Member of Scientific Council of the Institute of Ecology and Genetics of Microorganisms at the Ural Branch of the Russian Academy of Sciences.
Member of Dissertation Council at the Institute of Ecology and Genetics of Microorganisms at the Ural Branch of the Russian Academy of Sciences.
Member of Methodical Commission at the Faculty of Biology, Perm State University.
Member of editorial board of “Perm State University Herald” (Biology Series).
Member of State Attestation Commission at the Faculty of Biology, Perm State University.
Chairman of Perm Branch of Russian Scientific Society of Immunology.
Active Member of New York Academy of Sciences.
Active Member of the Russian Academy of Natural Sciences.
Member of Russian Scientific Society of Immunologists Presidium.
Leader of Scientific Projects
1. Soros Fund Grant “Support of Russian scientists”. 1993.
2. Russian Foundation for Basic Research 01-04-48116-a “Study of reproductive hormones role in the regulation of leucocytes apoptosis”. 2001-2002.
3. Russian Foundation for Basic Research 04-04-96064-р2004урал_a “Research into extrathymic differentiation of abT-lymphocytes during pregnancy”. 2004-2005.
4. Russian Foundation for Basic Research 10-04-06067-organisation and hosting of All-Russian conference “Reproduction Immunology”. 2010.
5. Russian Academy of Sciences Presidium Programme “Molecular and cell biology”, “Study of molecular mechanisms of immunomodulating activity of reproduction hormones”. 2009-2011.
Current Research Activities
Research into endocrine regulation of processes of differentiation and functioning of immune system’s cells. Complex study of molecular mechanisms of immunoregulatory activity of peptide and steroid reproductive hormones and immunomodulators. Research into the processes of extrathymic differentiation of T-lymphocytes in the pregnancy period.
Academic and other Awards
Note of acknowledgement from the Russian Academy of Sciences, 1999.
Honorary Certificate from the Russian Academy of Sciences, 2001.
Mechnikov Honorary Medal from the Russian Academy of Natural Sciences “For Practical Contribution to Promotion of Nation’s Health”, 2004.
Paul Erlich Medal from the European Academy of Natural Sciences “For Outstanding Achievements in Preventive and Social Medicine”, 2004.
Honorary Certificate from Perm State University, 2006.
Letter of acknowledgement from the Chairman of the Perm Krai Government, 2007.
Honorary Certificate from Perm State University, 2010.
Letter of acknowledgement from the Chairman of the Legislative Council of the Perm Krai, 2010.
Alexander Nevsky Medal of Order 3rd Class, 2010.
Total Number of Publications – 413.
133 scientific articles,
4 monographs,
1 study guide.
Selected Publications
1. Kevorkov N.N., Shilov Yu.I., Shirshev S.V., Chereshnev V.A. Reproduction hormones in the immunoregulation processes. Yekaterinburg: Nauka, 1993. 172 p. (In Russian)
2. Shirshev S.V. Mechanisms of Immune control of processes of reproduction. Yekaterinburg: Ural Branch of the Russian Academy of Sciences Publication, 1999. 381 p. (In Russian)
3. Shirshev S.V. Mechanisms of immune endocrine control of processes of reproduction. In 2 vols. Yekaterinburg: Ural Branch of the Russian Academy of Sciences Publication, 2002. Vol. 1. 430 p. (In Russian)
4. Shirshev S.V. Mechanisms of immune endocrine control of processes of reproduction. In 2 vols. Yekaterinburg: Ural Branch of the Russian Academy of Sciences Publication, 2002. Vol. 2. 585 p. (In Russian)
5. Shirshev S.V. Immunology of maternal-fetal interactions. Yekaterinburg: Ural Branch of the Russian Academy of Sciences Publication, 2009. 582 p. (In Russian)
6. Shirshev S.V., Kuklina Ye.M., Yarilin A.A. The role of reproduction hormones in the control of T-lymphocytes apoptosis // Biochemistry. 2003. Vol. 68, № 4. P.577-583. (In Russian)
7. Shirshev S.V., Orlova Ye.G. Molecular mechanisms of leptin regulation of functional activity of mononuclear phagocytes // Biochemistry. 2005. Vol. 70, № 8. P.1021-1029. (In Russian)
8. Shirshev S.V., Kuklina Ye.M., Maksimov A.Yu., Krapivina O.A., Parshakova N.S. Extrathymic rearrangement of the genes of abT-lymphocytes receptor during pregnancy // Ibid. Т.72, № 9. P.1207-1213. (In Russian)
9. Shirshev S.V. Immunoregulatory effects of prostaglandins of fetoplacental complex // Biology Bulletin Reviews. 2007. Vol. 127, № 4. P.358-371. (In Russian)
